厦门医学院基础医学部「转化医学中心」

转化医学中心简介

转化医学（translational medicine）是指将基础医学的研究, 能够直接和临床治疗上连结的一个新思维, 本中心成立宗旨是将基础研究的结果转化为临床实际应用，让实验室中所得的基础研究成果，可以迅速发展成为有价值的医疗成果。转化医学中心目前主要人员有2位,主要的研究方向为“锌与红细胞生成对透析病人贫血治疗”及“代谢相关疾病的研究”，目前共承担厅级项目4项，校级项目4项，发表高质量SCI论文10余篇。

研究方向

锌与红细胞生成及肾脏疾病相关研究(陈彦桦)

    糖尿病及其他代谢相关疾病的研究 (姚政源)

研究团队

研究成果——近5年发表期刊

1. Chen, Y. H.; Jeng, S. S.; Hsu, Y. C.; Liao, Y. M.; Wang, Y. X.; Cao, X.; Huang, L. J., In anemia zinc is recruited from bone and plasma to produce new red blood cells. Journal of inorganic biochemistry 2020, 210, 111172. (SCI, Impact factor: 3.212)

2. Feng, H. L.; Chen, Y. H.; Jeng, S. S., Effect of zinc supplementation on renal anemia in 5/6-nephrectomized rats and a comparison with treatment with recombinant human erythropoietin. International journal of molecular sciences 2019, 20, (20). (SCI, Impact factor: 4.556)

3. Chen, S. Z.; Chen, Y. J.; Chen, Y. H.; Yao, Z. Y., InP/ZnS quantum dots cause inflammatory response in macrophages through endoplasmic reticulum stress and oxidative stress. International journal of nanomedicine 2019, 14, 9577-9586. (SCI, Impact factor: 5.115)

4. Chen, Y. H.; Feng, H. L.; Jeng, S. S., Zinc supplementation stimulates red blood cell formation in rats. International journal of molecular sciences 2018, 19, (9). (SCI, Impact factor: 3.687)

5. Chen, Y. H.; Shiu, J. R.; Ho, C. L.; Jeng, S. S., Zinc as a signal to stimulate red blood cell formation in fish. International journal of molecular sciences 2017, 18, (1). (SCI, Impact factor: 3.226)

6. Chen, Y.H.; Chen, P.; Wang, Y.; Yang, C.-H.; Wu, X.; Wu, C.-J.; Luo, L.; Wang, Q.; Niu, C.; Yao, J.Y., Structural characterization and anti-inflammatory activity evaluation of chemical constituents in the extract of Trifolium repens L. Journal of Food Biochemistry 2019, 0, (0), e12981. (SCI, Impact factor:1.66 )

7. Chen P, Y. C., Yao J.Y., Xia J., Zheng W., Wu X, et al. , Anti-insulin resistance effects of diarylheptanoids and flavonoids from Myrica rubra leaves. Minerva Biotecnologica 2018, 30, 6. (SCI, Impact factor: 1.17)

8. Yao, J. Y.; Chen, J. K., Over-expression of DeltaNp63alpha facilitates rat corneal wound healing in vivo. Bioscience Biotechnology Biochemistry 2017, 81, (12), 2279-2284. (SCI, Impact factor: 1.06)

联系方式

负责人：姚政源

电话：18559665620